Ctbp ogdhl
WebFeb 25, 2024 · In a 15-year-old girl (BAB4852), born of consanguineous Turkish parents, with Yoon-Bellen neurodevelopmental syndrome (YOBELN; 619701), Yoon et al. (2024) identified a homozygous c.2333C-T transition (c.2333C-T, NM_018245) in exon 18 of the OGDHL gene, resulting in a ser778-to-leu (S778L) substitution at a conserved region in … WebAug 14, 2015 · The OGDHL promoter methylation pattern was assumed to provide a marker for differential diagnosis of CIMP+ (CpG island methylator phenotype) tumors, which display dense hypermethylation of the promoter region in many genes. Cell metabolic reprogramming is one of the cancer hallmarks. Glycolysis activation, along with …
Ctbp ogdhl
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WebMar 18, 2024 · In particular, a non-synonymous single nucleotide variation in the oxoglutarate dehydrogenase-like (OGDHL) gene, rs2293239 (p.Asn725Ser), was identified as one of the major driving genetic forces … WebThe pro-metastatic role of OGDHL downregulation is most likely attributed to its upregulation of HIF-1α transactivation activity and the protein stabilization by promoting the accumulation of L-2-HG to prevent the activity of HIF-1α prolyl hydroxylases, which subsequently causes an epithelial–mesenchymal transition process in HCC cells.
WebNov 13, 2007 · The OGDHC complex comprises multiple copies of three catalytic enzyme components, the 2-oxoglutarate dehydrogenase (OGDH/E1), the dihydrolipoamide … WebApr 7, 2024 · Identification of Candidate OGDHL-Targeting miRNAs. Regarding OGDHL might play an important role in DCM, we then use the miRWalk 2.0 software to predict …
WebPaperwork Reduction Act Notice: An agency may not conduct or sponsor an information collection and a person is not required to respond to this information request unless it … WebMay 1, 2024 · To further examine the functional impacts of OGDHL in hepatoma cell progression, we constructed shRNA-OGDHL-knockdown clones (sh-A and sh-B) in Bel …
WebOGDHL has 3,312 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 66 datasets. Click the + buttons to view associations for ...
WebAug 5, 2024 · OGDHL oxoglutarate dehydrogenase L Gene ID: 55753, updated on 5-Aug-2024 Gene type: protein coding Also known as: YOBELN See all available tests in GTR for this gene Go to complete Gene record for OGDHL Go to Variation Viewer for OGDHL variants Summary can powdered milk be used as coffee creamerWebThe overexpression of OGDHL also markedly suppressed the growth of HCC-LM3/OGDHL xenograft tumors in immunodeficient mice (p = 0.014; Figure 8C,D); these findings were … flamin foodsWebTissue proteome. GENERAL INFORMATIONi. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. OGDHL. can powdered creamer be used as milkWebConclusion: Our findings established that silencing of OGDHL contributed to HCC development and survival by regulating glutamine metabolic pathways. OGDHL is a … flaming acrylicWebCBP appreciates your assistance in strengthening global supply chain security and commitment to trade compliance. As you begin your application for CBP's Trusted … flaming adventures robloxWebJan 12, 2024 · OGDHL is predicted to be a thiamine diphosphate-dependent 2-oxo acid dehydrogenase ( EC 1.2.4.2) for reduction of protein-bound lipoyl groups ( Bunik and Degtyarev, 2008 ). OGDHL encodes a rate-limiting enzyme in the Krebs cycle that plays a pivotal role in mitochondrial metabolism ( Yap et al., 2024 ). Cloning and Expression flaming aces tattooWebJan 25, 2024 · The ketoglutarate dehydrogenase complex (KGDHC) consists of three different subunits encoded by OGDH (or OGDHL), DLST, and DLD, combined in different stoichiometries. DLD subunit is shared between KGDHC and pyruvate dehydrogenase complex, branched-chain alpha-keto acid dehydrogenase complex, and the glycine … can powdered pectin be substituted for liquid